Back to Study: Effect of dietary additives on intestinal permeabi...
correlational
mixed effect
When fruit flies eat normal food, removing their gut bacteria makes their gut more leaky, but when they eat a lot of sugar, removing gut bacteria doesn't change gut leakiness.
Scientific Claim
Antibiotic treatment to disrupt the gut microbiome increases intestinal permeability in Drosophila melanogaster fed a control diet but not in those fed a high-sugar diet.
Source Excerpt
“Antibiotic feeding led to increased gut permeability during control sugar feeding conditions (Fig. 6G) but not during HS feeding (Fig. 6H) on this conventional diet.”
Evidence from Studies
Supporting Studies
Effect of dietary additives on intestinal permeability in both Drosophila and a human cell co-culture
Cannot Determine
View study →3%
Evidence Assessment
Supported
The study measured Smurfing in flies with and without antibiotics on control and high-sugar diets, finding that antibiotics increased permeability only in control diet flies.