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When heart and blood vessel fat from heart failure patients was treated with methylene blue, the amount of harmful reactive molecules (like hydrogen peroxide) it produced went down.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Methylene blue reduces monoamine oxidase expression and oxidative stress in human cardiovascular adipose tissue

Cross-Sectional Study
Human
2025 Apr

The study found that a chemical called methylene blue, when applied to fat tissue around the heart of heart failure patients, lowered harmful oxygen molecules that damage cells—exactly what the claim says.

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No contradicting evidence found

Source Study

Methylene blue reduces monoamine oxidase expression and oxidative stress in human cardiovascular adipose tissue

Score: 33
DOI: 10.1007/s11010-024-05092-z

Similar Assertions

When fat tissue around the heart and blood vessels from heart failure patients was soaked in a small amount of methylene blue for a day, the levels of a specific enzyme (MAO-A) that makes harmful molecules went down.

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The fat directly on the heart makes more harmful molecules than the fat around the big blood vessels, even without any treatment.

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77%

The blue dye methylene blue cut the amount of a harmful chemical (hydrogen peroxide) in heart and blood vessel fat by about half when tested in the lab.

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When fat tissue around the heart and blood vessels was soaked in a blue dye called methylene blue for a day in the lab, it made less of a harmful enzyme and produced fewer damaging chemicals, which might help explain how the dye could protect cells.

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