When breeder hens eat a diet rich in omega-3 fatty acids, the eggs they lay contain more omega-3 fats, and the chicks that hatch from those eggs have higher omega-3 and lower omega-6 fatty acid...
Mechanism
Synthesis from 1 study
The mom hen's diet changes the fats in her eggs. The baby chick uses those fats to build its own body, replacing some of its natural fats with the ones from the egg. This swap changes the signals the chick's body sends, making them less inflammatory.
Most probable mechanism
When a hen eats more omega-3 fats, those fats go into her eggs. When the chick hatches, it uses those fats to build its own body tissues, especially in the heart, liver, brain, and lungs. The omega-3 fats replace some of the omega-6 fats in the chick's cell membranes. This change causes the chick's body to make different signaling molecules that are less inflammatory than the ones made when omega-6 fats are dominant.
Dietary omega-3 fatty acids from the breeder hen are absorbed and incorporated into egg yolk phospholipids
Egg-derived omega-3 fatty acids are absorbed by the developing chick and incorporated into tissue phospholipids of cardiac, liver, brain, and lung cells
Increased omega-3 fatty acid content in tissue membranes competes with and displaces long-chain omega-6 fatty acids, reducing their availability as enzymatic substrates
Cyclooxygenase enzymes metabolize omega-3 fatty acids instead of omega-6 fatty acids, producing thromboxane A3 and prostaglandin E3 instead of thromboxane A2 and prostaglandin E2
Reduced prostaglandin E2 and altered thromboxane profile decrease pro-inflammatory signaling in chick tissues
Evidence from Studies
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