Claim
Strong Support
quantitative
Analysis v3

In people trained in resistance exercise, performing lateral raises with dumbbells or cables twice a week for 8 weeks results in a 3.3% to 4.6% increase in the thickness of the side shoulder muscle.

60
Pro
0
Against

Mechanism

Synthesis from 1 study

How it works

When the side shoulder muscle is stretched under heavy load, the tension inside the muscle fibers turns on signals that make more contractile proteins. These proteins build up over time, making the muscle thicker. This happens whether the weight feels heavier at the start or end of the movement, as...

Most probable mechanism

In Simple Terms

When the side shoulder muscle is stretched while under load, the internal tension activates signals that tell the muscle to build more contractile proteins, making the muscle fibers thicker over time. This happens whether the resistance is heavier at the start or end of the movement, as long as the muscle is fully stretched and worked to exhaustion.

Causal chain
1

The lateral deltoid muscle is stretched to its lengthened position during shoulder abduction, placing the sarcomeres on the descending limb of the length-tension relationship and increasing passive tension through titin filament extension.

Supported by evidence
which leads to
2

Mechanical tension from stretched muscle fibers activates intracellular mechanosensing pathways, including titin-based signaling, which triggers phosphorylation of mTOR and MAPK kinases.

Indirect evidence only
which leads to
3

Activated signaling cascades increase ribosomal activity and mRNA translation, leading to elevated synthesis of myofibrillar proteins such as actin and myosin.

Indirect evidence only
which leads to
4

Protein synthesis exceeds proteolytic breakdown, resulting in net accumulation of contractile proteins within muscle fibers.

Verified by multiple studies
which leads to
5

Increased myofibrillar protein content expands muscle fiber cross-sectional area, which is measured as increased muscle thickness.

Verified by multiple studies

Evidence from Studies

Supporting (1)

60

Community contributions welcome

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Sign up to see full verdict