When scientists gave a specific fat chemical (15-HETE) to mice whose heat production was blocked, it brought back their ability to burn fat and generate heat, even if the bacteria or enzyme blocking it were still present.

Pro

Against

Evidence from Studies

Supporting (1)

Community contributions welcome

Adipose Tissue‐Resident <i>Sphingomonas Paucimobilis</i> Suppresses Adaptive Thermogenesis by Reducing 15‐HETE Production and Inhibiting AMPK Pathway

Cohort Study

Human

2024 Dec

When mice have a certain gut bacteria or inflammation, they can’t stay warm well because they make less of a helpful molecule called 15-HETE. Giving them more of this molecule fixes their body’s ability to generate heat and burn fat.

Contradicting (0)

Community contributions welcome

No contradicting evidence found

Source Study

Adipose Tissue‐Resident <i>Sphingomonas Paucimobilis</i> Suppresses Adaptive Thermogenesis by Reducing 15‐HETE Production and Inhibiting AMPK Pathway

Score: 53

DOI: 10.1002/advs.202310236

Similar Assertions

When scientists grew fat cells with this specific bacteria (Sphingomonas), the cells stopped making a key fat-burning chemical and heat-producing proteins—but when they used a different common bacteria (E. coli), nothing changed.

83%

In mice, a type of gut bacteria called Sphingomonas paucimobilis moves to belly fat during inflammation and blocks the body’s ability to burn calories for heat by interfering with a key fat-burning chemical and its signaling pathway.

75%