Health Claims

Some diabetes and weight-loss drugs like liraglutide and semaglutide might harm unborn babies, but it's probably because they make pregnant animals eat less and lose weight, not because they directly cause birth defects.

Some diabetes drugs like liraglutide and semaglutide might help pregnant women with blood sugar problems by lowering their blood sugar levels and improving how their body handles insulin.

A week of Exendin-4 treatment helps restore brain cells in the anxiety center of mice and calms their overactivity.

The brain's anxiety control center has more receptors for GLP-1 on 'go' brain cells than 'stop' cells, meaning GLP-1 mainly affects activation, not calming.

Heroin use damages certain brain cells in a mood center in mice, but doesn't cause anxiety while they're using—problems show up only when they stop.

When mice go through heroin withdrawal, a brain chemical called GLP-1 increases in a brain circuit linked to anxiety, and this is connected to more anxious behavior.

Giving a drug called Exendin-4 for a week helps reduce anxiety in male mice going through heroin withdrawal, possibly by helping brain cells in a mood-related area heal.

So far, only one in three studies has found that diabetes drugs called GLP-1 agonists might help with depression, so the proof isn't strong or clear yet.

Some diabetes drugs called GLP-1 agonists might help with depression symptoms, based on a few studies — but the results aren't clear-cut and more research is needed.

Some diabetes drugs called GLP-1 RAs might help with depression in animals — most lab studies saw fewer signs of depression, and scientists think it’s because these drugs change brain inflammation, brain cell connections, and brain chemicals.

Older Black male veterans with type 2 diabetes have similar blood sugar levels no matter which common diabetes medicine they take—like metformin, insulin, or newer drugs like Ozempic or Farxiga.

Older Black male veterans with diabetes, liver issues, and depression who take SGLT2 inhibitor pills tend to weigh less than those on GLP-1 shots, even though both types of medicine usually help people lose weight.

In older Black male veterans with diabetes, fatty liver, and depression, how bad their depression is doesn't seem to be linked to how much scarring their liver has — especially if they're taking certain diabetes meds like GLP-1 drugs or SGLT2 inhibitors.

Older Black male veterans with diabetes, fatty liver, and depression who take GLP-1 drugs like semaglutide have slightly lower depression scores than those on SGLT2 drugs, but the difference isn’t big enough to be sure it’s not just by chance.

Older Black male veterans with diabetes, fatty liver, and depression who take GLP-1 drugs (like Ozempic) seem to have less liver scarring than those on SGLT2 drugs, based on a blood test score — but the difference isn’t strong enough to be sure it’s not just by chance.

If you have schizophrenia and gain weight from your medication, taking GLP-1 drugs (like those used for diabetes) probably won’t make your mental symptoms worse — and might actually help you feel better overall, even if it doesn’t fix the main symptoms of schizophrenia.

People with obesity who take certain diabetes drugs like exenatide or dulaglutide might end up drinking less alcohol — one study says exenatide cuts alcohol use by over a kilogram in a month, and dulaglutide by about 1.4 drinks a day.

Certain diabetes and weight-loss drugs like semaglutide and dulaglutide might help reduce binge eating, especially in people with binge eating disorder, by affecting how the brain handles rewards.

Weight-loss drugs like Ozempic don’t seem to raise suicide risk for most people, but there might be a warning sign for those also taking antidepressants or anxiety meds.

People with type 2 diabetes who take GLP-1 drugs like Ozempic might feel a little better emotionally, but the mood boost is small and doesn’t show up in every study.

Some diabetes drugs called GLP-1 agonists might help ease depression in people, based on early studies — but we’re not sure yet because the research has some flaws.

Taking diabetes drugs called GLP-1 receptor agonists might slightly improve mood in people, whether or not they have diabetes, based on depression score changes in studies.

People with Type 2 diabetes who take GLP-1 drugs like semaglutide or liraglutide might feel a little less depressed, even if that’s not why they’re taking the medicine.

These diabetes and weight-loss drugs might be affecting the parts of your brain that control how you feel emotionally.