Browse evidence-based analysis of health-related claims and assertions
Log in to see full claim details, scientific mechanisms, and cited studies.
During intense military training, women tend to eat more calories than men, but both end up with similar energy deficits, suggesting their bodies may process or use energy differently.
When male and female soldiers undergo the same intense military training for over 61 days with similar calorie deficits, men tend to lose more total body weight, while women preserve more muscle and...
Many women who gain too much weight during pregnancy still carry at least 4.6 to 5 kilograms of that weight six months after giving birth, even when they receive structured lifestyle support and...
Mothers who have had depression or anxiety in the past are less likely to regularly record their mood and stress levels on a phone app after giving birth, indicating that past mental health struggles...
For mothers who gained a lot of weight during pregnancy, using a fitness app to track daily steps after giving birth does not lead to greater weight loss or less remaining weight six months later.
For mothers who gained too much weight during pregnancy, regularly tracking their mental health using a mobile app in the first six months after giving birth is linked to a small decrease in the...
Mothers who logged their weight more often using a mobile app after giving birth, within 6 weeks to 6 months postpartum, lost slightly more weight and were less likely to retain 5 kg or more compared...
Overweight women who perform high-intensity circuit training for 5–12 MET-hours per week can achieve significant fat loss and improved metabolic health, even though this amount of exercise is less...
After stopping 10 months of intense circuit training, overweight women lose some of their fat loss and fitness improvements over 5 months, but not all of it—body fat goes up slightly and aerobic...
After 10 months of high-intensity circuit training, sedentary overweight women experienced a 27% increase in aerobic capacity and muscle strength, and about half of those gains remained after...
In overweight women, high-intensity circuit training can raise the number of calories burned at rest by 6–10%, which helps reduce body fat over time even without changing food intake, due to...
In previously sedentary, overweight or class I obese women, a structured 10-month exercise program involving high-intensity circuit training three times per week is associated with a reduction in...
For middle-aged men who lift weights and are eating fewer calories, switching between a low-carb ketogenic diet and a higher-carb diet does not change their blood fat levels or blood sugar levels.
Among middle-aged men who lift weights and eat fewer calories, levels of testosterone rise and insulin levels fall, whether they follow a ketogenic diet or a different type of low-calorie diet.
Among middle-aged men who lift weights and are eating fewer calories, a ketogenic diet that keeps ketones high does not lead to better preservation of muscle strength or body composition than a...
In mice, a specific thyroid hormone receptor called TRα1 is not needed for thyroid hormone to affect energy production in fast-twitch muscle fibers, but it is required for thyroid hormone to increase...
In mice, blocking a specific thyroid hormone receptor in muscle tissue leads to higher levels of sarcolipin mRNA in both slow- and fast-twitch muscle fibers, which may relate to how muscles generate...
When thyroid hormone receptor alpha 1 is removed from the skeletal muscle of mice, the slow-twitch muscle fibers in the soleus muscle become more dominated by type I fibers and fewer type IIA fibers,...
In mice, the thyroid hormone T3 raises body temperature even when the thyroid hormone receptor TRα1 is not functional in skeletal muscle, indicating that the temperature increase does not depend on...
In mice, the thyroid hormone T3 raises overall energy use by acting on a specific receptor, TRα1, in skeletal muscle. When this receptor is disabled in muscle tissue, the increase in energy use does...
When people lose weight, their bodies adjust how many calories they burn, and this adjustment can differ greatly from person to person—some burn hundreds fewer calories, others burn hundreds more...
People who reach their weight loss goal faster or slower than expected may do so in part because of how their metabolism adjusts during weight loss, even when accounting for how strictly they follow...
After losing 16% of their body weight, women who are overweight and have not gone through menopause tend to burn about 46 fewer calories per day at rest than what would be expected based on their...
In premenopausal women with overweight, how closely they follow their diet is the most important factor in determining how quickly they reach their weight loss goals, more so than their metabolism,...