Does Carnosine Supplement Help with Blood Sugar and Cholesterol?

Original Title

Effect of carnosine supplementation on lipid profile, fasting blood glucose, HbA1C and insulin resistance: A systematic review and meta-analysis of long-term randomized controlled trials.

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Summary

Researchers looked at 4 studies with 184 people to see if taking carnosine supplements helps with metabolic health markers. They found that carnosine lowered long-term blood sugar (HbA1C) but did not significantly change other markers like triglycerides, insulin resistance, or cholesterol.

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Surprising Findings

Carnosine lowers long-term blood sugar but doesn't improve insulin resistance

You'd expect that if HbA1C drops, insulin sensitivity would also improve - but the study found no significant change in HOMA-IR, a measure of insulin resistance. This disconnect is unexpected.

Practical Takeaways

If you have metabolic issues and are considering carnosine supplements, know that it may help with long-term blood sugar (HbA1C) but likely won't improve insulin resistance, cholesterol, or triglyceride levels.

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