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The Study

Vitamin D supplementation to prevent acute respiratory infections: systematic review and meta-analysis of stratified aggregate data

In simple terms

This study combines results from many smaller experiments where vitamin D was tested against fake pills. It shows that overall, vitamin D doesn't clearly prevent colds and flu, but it might help some people like kids or those taking daily small doses.

45%

Analysis score

45/ 100

Maximum 100 for a systematic review with meta-analysis.

Where the score came from

Reporting0
Methodology0
Publication100
Statistical100
Study type (basis of the score)
Systematic Review with Meta-Analysis
Level 1a - Systematic review of RCTs
What’s the bottom line?

Scientists looked at many studies to see if taking vitamin D stops people from getting colds.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Reviews of RCTs (Meta-analyses)
Level 1a
45

45 / 100

Quality score

The highest quality evidence. Systematic reviews and meta-analyses that pool randomized controlled trials, giving the most reliable summary of experimental evidence.

Can establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1For most people, vitamin D doesn't prevent colds, but it's safe to take.
  2. 2Taking vitamin D did not stop colds overall.
  3. 3In some groups like kids, it might help a little, but it's not certain.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

The lancet. Diabetes & endocrinology

Year

2024

Authors

David A. Jolliffe, C. Camargo, J. Sluyter, M. Aglipay, J. Aloia, P. Bergman, Heike A. Bischoff-Ferrari, Arturo Borzutzky, V. Bubes, C. T. Damsgaard, Francine M. Ducharme, G. Dubnov-Raz, S. Esposito, D. Ganmaa, C. Gilham, A. Ginde, Inbal Golan-Tripto, E. Goodall, C. Grant, C. Griffiths, A. Hibbs, W. Janssens, A. V. Khadilkar, I. Laaksi, Margaret T. Lee, Mark Loeb, Jonathon L. Maguire, Paweł Majak, S. Manaseki-Holland, J. Manson, David T. Mauger, David Murdoch, Akio Nakashima, Rachel E Neale, H. Pham, Christine Rake, Judy R Rees, Jenni Rosendahl, Robert Scragg, Dheeraj Shah, Yoshiki Shimizu, S. Simpson-Yap, G Trilok Kumar, M. Urashima, A. Martineau

Open Access
13 citations
Analysis v5
Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.