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Mirabegron boosts body's fat-burning and blood sugar control in healthy women

Original Title

Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity.

doi:10.1172/jci131126
25%

Lower Quality

Methodology score · 25/100

Cross Sectional Human
Fit Body Science breakdown

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What’s the bottom line?

A drug called mirabegron, usually for bladder issues, was given to healthy women for 4 weeks. It helped their bodies burn more energy, improved blood sugar control, and raised good cholesterol and other healthy markers — without changing weight.

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Publication

Authors

O'Mara AE, Johnson JW, Linderman JD, Brychta RJ, McGehee S, Fletcher LA, Fink YA, Kapuria D, Cassimatis TM, Kelsey N, Cero C, Sater ZA, Piccinini F, Baskin AS, Leitner BP, Cai H, Millo CM, Dieckmann W, Walter M, Javitt NB, Rotman Y, Walter PJ, Ader M, Bergman RN, Herscovitch P, Chen KY, Cypess AM