Mirabegron boosts body's fat-burning and blood sugar control in healthy women
Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
A drug called mirabegron, usually for bladder issues, was given to healthy women for 4 weeks. It helped their bodies burn more energy, improved blood sugar control, and raised good cholesterol and other healthy markers — without changing weight.
Surprising Findings
Metabolic improvements without weight loss
Most people assume that improving metabolism or insulin sensitivity requires weight loss. But this study found significant improvements in BAT activity, energy expenditure, and blood sugar control — while body weight and composition remained unchanged.
Practical Takeaways
Consider discussing mirabegron with your doctor if you have insulin resistance or prediabetes — especially if lifestyle changes haven’t helped.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
A drug called mirabegron, usually for bladder issues, was given to healthy women for 4 weeks. It helped their bodies burn more energy, improved blood sugar control, and raised good cholesterol and other healthy markers — without changing weight.
Surprising Findings
Metabolic improvements without weight loss
Most people assume that improving metabolism or insulin sensitivity requires weight loss. But this study found significant improvements in BAT activity, energy expenditure, and blood sugar control — while body weight and composition remained unchanged.
Practical Takeaways
Consider discussing mirabegron with your doctor if you have insulin resistance or prediabetes — especially if lifestyle changes haven’t helped.
Publication
Journal
The Journal of clinical investigation
Year
2020
Authors
Alana O'mara, James W. Johnson, J. Linderman, R. Brychta, Suzanne McGehee, Laura A. Fletcher, Yael A Fink, D. Kapuria, Thomas M. Cassimatis, N. Kelsey, C. Cero, Z. A. Sater, Francesca Piccinini, Alison S. Baskin, Brooks P. Leitner, H. Cai, C. Millo, W. Dieckmann, M. Walter, N. Javitt, Y. Rotman, P. Walter, M. Ader, R. Bergman, P. Herscovitch, Kong Y. Chen, A. Cypess
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Claims (6)
Excess visceral, liver, and intramuscular fat represent a serious metabolic dysfunction that is not solely due to lack of discipline, and reducing these fat depots improves metabolic function and overall well-being, with muscle quality being a key factor in longevity.
Healthy women who took mirabegron pills for four weeks had more active brown fat, which helps burn calories. This finding is from the abstract summary - full study details were not available
Taking mirabegron for four weeks made healthy women burn more calories at rest without losing weight. This finding is from the abstract summary - full study details were not available
Mirabegron treatment raised levels of good cholesterol and bile acids in healthy women after four weeks. This finding is from the abstract summary - full study details were not available
After four weeks of mirabegron, healthy women had 35% more adiponectin, a hormone that helps regulate blood sugar. This finding is from the abstract summary - full study details were not available