quantitative
Analysis v1
Strong Support
A drug called alirocumab, given as a 75mg shot every couple of weeks, lowered bad cholesterol by almost half in people at high risk for heart problems over six months — a bit less than another similar drug, evolocumab.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Proprotein convertase subtilisn/kexin type 9 inhibitors and small interfering RNA therapy for cardiovascular risk reduction: A systematic review and meta-analysis
Systematic Review With Meta-Analysis
Human
2023The study shows that Alirocumab lowers bad cholesterol by 46.35%, just like the claim says, and it works a bit less than another drug called Evolocumab.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.