A shot of a drug called AMG 145 can quickly lower bad cholesterol—by up to 64% in just a few days—especially when given at higher doses, and it works by targeting a specific protein in the body.

A drug called AMG 145, when given as a weekly shot at 35 mg or more, can cut bad cholesterol by up to 81% in people already on cholesterol meds, and the effect lasts through the week—so it might work well even if given every other week.

A drug called AMG 145 seems to lower a harmful type of cholesterol called Lp(a) by up to half in people already taking cholesterol meds, and it might work in a new way doctors haven’t seen before.

A shot called AMG 145, given once a month, can cut bad cholesterol by more than 60% in people already on cholesterol meds — and it stays effective the whole month.

A drug called AMG 145, when given every two weeks, cuts bad cholesterol by about three-quarters in people with high cholesterol who are already on strong meds or have a genetic form of the condition — even when their options are limited.

A drug called AMG 145 can lower a harmful blood protein linked to heart disease by up to 59% in people with high cholesterol who are already taking statins, and it seems to do more than just lower bad cholesterol.