If you've lost weight on a low-calorie diet, keeping it off might be easier if you combine aerobic exercise with the drug liraglutide — this combo seems to help burn more fat while preserving muscle...

If you lose weight on a low-calorie diet, you're more likely to keep it off if you combine liraglutide with aerobic exercise, rather than doing just one of those things — the exercise seems to boost how well the medication works over time.

In adults with obesity and prediabetes, a 14-week diet creating a 390 kcal daily deficit leads to more weight loss and a greater improvement in body fat-to-muscle ratio than daily 1.8 mg liraglutide.

Adults with obesity who took a drug called liraglutide for 6 months, while eating less and exercising, lost more deep belly fat than those who didn’t — and the study says this medicine might help burn that stubborn fat better.

In adults with obesity and prediabetes, losing weight through calorie reduction maintains muscle mass, but taking 1.8 mg of liraglutide daily causes muscle mass to decrease.