If you lose weight on a low-calorie diet, you're more likely to keep it off if you combine liraglutide with aerobic exercise, rather than doing just one of those things — the exercise seems to boost how well the medication works over time.

If you've lost weight on a low-calorie diet, keeping it off might be easier if you combine aerobic exercise with the drug liraglutide — this combo seems to help burn more fat while preserving muscle better than doing just one or the other over a year.

Giving mice both nicotine and a diabetes drug called liraglutide together helps them lose weight by making them eat less and burn more calories.