Apelin activates a key energy-sensing enzyme in muscles, which helps reduce fat buildup and improve metabolism.

13

Pro

0

Against

Evidence from Studies

Supporting (1)

13

Community contributions welcome

13

Apelin Treatment Increases Complete Fatty Acid Oxidation, Mitochondrial Oxidative Capacity, and Biogenesis in Muscle of Insulin-Resistant Mice

Randomized Controlled Trial

Animal

2012 Feb

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Source Study

Apelin Treatment Increases Complete Fatty Acid Oxidation, Mitochondrial Oxidative Capacity, and Biogenesis in Muscle of Insulin-Resistant Mice

Score: 13

DOI: 10.2337/db11-0100

Similar Assertions

Apelin's benefits for fat burning and mitochondria in muscles only work when AMPK is active, as shown in genetically modified mice.

13

0

88%

Apelin-treated mice burn fat more completely in their muscles compared to placebo-treated mice, reducing harmful fat byproducts.

13

0

86%

Giving apelin to obese, insulin-resistant mice for a month helps them lose body fat and lowers their blood sugar levels compared to mice given a placebo.

13

0

86%

Apelin lowers blood fat levels and helps mice process sugar better, improving overall metabolic health.

13

0

86%

Apelin reduces harmful fat byproducts in muscles, which helps muscles take up more glucose in response to insulin.

13

0

83%