Even though taking NR or NMN boosts a molecule called NAD+ in the blood, we don’t actually have solid proof it makes people stronger, healthier, sharper, or more energetic.

The study gave people a supplement called NR, which raised NAD+ levels, but didn’t clearly improve brain function or energy compared to a placebo. This supports the idea that just boosting NAD+ doesn’t necessarily make you feel or perform better.

The study looked at whether NR and NMN supplements help older adults' muscles work better. It found little to no real improvement, which supports the idea that these supplements don’t clearly boost muscle or physical performance, even though they raise NAD+ levels.

The study looked at whether taking NMN helps with blood sugar and fat levels, and found no real benefit. This supports the idea that even though NMN raises NAD+ levels, it doesn’t clearly improve health.

The study shows that NMN raises NAD+ levels in the blood, but it doesn’t test whether this leads to better muscle, brain, or overall physical health. So, it doesn’t prove that feeling stronger or healthier happens from taking it.

The study shows that while NR and NMN raise NAD+ levels in people, they don’t consistently improve energy, muscles, metabolism, or brain function. This matches the claim that we don’t have strong proof these supplements make a real difference in how people feel or perform.