Mice with a specific genetic modification that causes heart failure had about 30% worse heart pumping ability compared to normal mice.

16

Pro

0

Against

Evidence from Studies

Supporting (1)

16

Community contributions welcome

16

N‐acetylcysteine attenuates the development of cardiac fibrosis and remodeling in a mouse model of heart failure

Randomized Controlled Trial

Animal

2016 Apr

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Source Study

N‐acetylcysteine attenuates the development of cardiac fibrosis and remodeling in a mouse model of heart failure

Score: 16

DOI: 10.14814/phy2.12757

Similar Assertions

Mice with a specific genetic modification that causes heart failure had more than double the oxidative stress in their heart cells compared to normal mice.

16

0

76%

Giving the antioxidant NAC to mice with heart failure didn't help their heart's pumping ability improve, even though it reduced some scarring.

16

0

75%

Mice with a specific genetic modification that causes heart failure had more than double the scarring in their heart blood vessels and tissue compared to normal mice.

16

0

73%