MOTS-c changed the activity of genes involved in fat metabolism in the muscles of immobilized mice.

16

Pro

0

Against

Evidence from Studies

Supporting (1)

16

Community contributions welcome

16

Mitochondrial-derived microprotein MOTS-c attenuates immobilization-induced skeletal muscle atrophy by suppressing lipid infiltration.

Randomized Controlled Trial

Animal

2024 Mar 1

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Source Study

Mitochondrial-derived microprotein MOTS-c attenuates immobilization-induced skeletal muscle atrophy by suppressing lipid infiltration.

Score: 16

DOI: 10.1152/ajpendo.00285.2023

Similar Assertions

MOTS-c changed the activity of genes related to fat metabolism and PPAR pathways in the muscles of immobilized mice, which may affect how fat builds up in muscle tissue.

16

0

90%

Mice given MOTS-c had more ANGPTL4 protein in their muscles and less fatty acids, which may help prevent muscle damage from fat buildup.

16

0

72%

Obese mice treated with MOTS-c had lower levels of ANGPTL4 in their muscles, which may help prevent fat buildup.

8

0

70%