Taking a daily pill of hyaluronic acid for 3 months can make your wrinkles look about 19% smaller than if you didn’t take it, according to this claim.
Claim Language
Language Strength
definitive
Uses definitive language (causes, prevents, cures)
The claim uses the verb 'significantly reduces', which implies a direct, measurable, and certain cause-effect relationship, characteristic of definitive language. The specific percentage (18.8%) further reinforces the assertion of a precise and conclusive outcome.
Context Details
Domain
medicine
Population
human
Subject
Oral hyaluronic acid supplementation (120 mg/day)
Action
reduces
Target
winkle depth by approximately 18.8% over 12 weeks compared to placebo in middle-aged adults
Intervention Details
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.
Evidence from Studies
Supporting (1)
Oral intake of a new full-spectrum hyaluronan improves skin profilometry and ageing: a randomized, double-blind, placebo-controlled clinical trial
The study gave people a hyaluronic acid pill and found their wrinkles got 18.8% shallower — just like the claim says — even though they took a slightly higher dose for a shorter time.