Taking a daily supplement of hyaluronan for 12 weeks can make your facial wrinkles look about 11.5% less noticeable, compared to not taking anything, if you're a healthy Asian adult between 35 and 64.
Claim Language
Language Strength
definitive
Uses definitive language (causes, prevents, cures)
The claim uses 'significantly reduces', which implies a direct, measurable, and certain cause-effect relationship, not a possibility or correlation. 'Significantly' reinforces statistical certainty, and 'reduces' is a strong causal verb.
Context Details
Domain
medicine
Population
human
Subject
Healthy Asian adults aged 35–64
Action
reduces
Target
facial wrinkle severity by 11.5%
Intervention Details
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.
Evidence from Studies
Supporting (1)
Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study
This study gave people 120 mg of hyaluronan daily for 12 weeks and found their wrinkles got noticeably better compared to those who took a fake pill — just like the claim says.