Taking a daily supplement of hyaluronan for 12 weeks can make your face more hydrated, with a noticeable 10.9% boost in skin moisture compared to not taking it—this also helps your skin stay protected and lose less water.
Claim Language
Language Strength
definitive
Uses definitive language (causes, prevents, cures)
The claim uses definitive language such as 'significantly improves', 'increasing', 'enhances', and 'reduces', which imply direct cause-and-effect relationships rather than possibilities or associations.
Context Details
Domain
medicine
Population
human
Subject
Healthy Asian adults aged 35–64
Action
ingestion
Target
120 mg/day hyaluronan for 12 weeks
Intervention Details
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.
Evidence from Studies
Supporting (1)
Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study
This study gave people 120 mg of hyaluronan daily for 12 weeks and found their skin got much more hydrated and lost less water, just like the claim says.