Can swallowing a pill make your skin smoother?
Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
The biggest elasticity improvement (38%) happened at the waist, not the face.
Most people assume oral supplements only affect the face or areas with high blood flow — but this shows systemic skin benefits, even in less visible areas.
Practical Takeaways
Try a 120 mg/day oral hyaluronan supplement for 12 weeks — look for 'Hyabest®' or 'high-purity sodium hyaluronate' on labels.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
The biggest elasticity improvement (38%) happened at the waist, not the face.
Most people assume oral supplements only affect the face or areas with high blood flow — but this shows systemic skin benefits, even in less visible areas.
Practical Takeaways
Try a 120 mg/day oral hyaluronan supplement for 12 weeks — look for 'Hyabest®' or 'high-purity sodium hyaluronate' on labels.
Publication
Journal
Nutrients
Year
2021
Authors
Tzu-Fang Hsu, Zi-Rong Su, Yao-Hao Hsieh, Ming-Fu Wang, Mariko Oe, Ryosuke Matsuoka, Y. Masuda
Related Content
Claims (6)
Taking a daily supplement of sodium hyaluronate for 3 months can make your face skin noticeably more hydrated—about 11.5% more—than if you didn’t take it.
Taking a daily supplement of hyaluronan for 12 weeks can make your face more hydrated, with a noticeable 10.9% boost in skin moisture compared to not taking it—this also helps your skin stay protected and lose less water.
Taking a daily supplement of hyaluronan for 12 weeks can make your skin feel tighter and more bouncy on your forehead, arms, and waist—especially at your waist, where it improved by 38% compared to people who didn’t take it.
Taking a daily supplement of hyaluronan for 12 weeks can make your facial wrinkles look about 11.5% less noticeable, compared to not taking anything, if you're a healthy Asian adult between 35 and 64.
Taking a daily supplement of hyaluronan for 12 weeks can help your skin hold onto more moisture, making your face less dry — like a natural moisture lock.