Taking a daily supplement of sodium hyaluronate for 3 months can make the fine lines around your eyes noticeably smoother—by about 1 in 8 to 1 in 7—starting as soon as one month in.

Pro

Against

Evidence from Studies

Supporting (1)

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Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults

Randomized Controlled Trial

Human

2025 Dec 20

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults

Score: 77

DOI: 10.1038/s41598-025-32758-5

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