Taking a daily supplement of sodium hyaluronate for 3 months can make the fine lines around your eyes noticeably smoother—by about 1 in 8 to 1 in 7—starting as soon as one month in.
Claim Language
Language Strength
definitive
Uses definitive language (causes, prevents, cures)
The claim uses the verb 'causes,' which implies a direct, deterministic effect rather than a possibility or association. This word asserts a cause-and-effect relationship without hedging.
Context Details
Domain
medicine
Population
human
Subject
Oral sodium hyaluronate (120 mg/day for 12 weeks)
Action
causes
Target
a significant reduction in periorbital wrinkle depth by approximately 12–15% in healthy Caucasian adults
Intervention Details
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.
Evidence from Studies
Supporting (1)
Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults
This study gave people 120 mg of sodium hyaluronate daily for 12 weeks and found their under-eye wrinkles got noticeably smaller, starting after just one month—exactly what the claim says.