Taking a daily supplement of sodium hyaluronate for 3 months may help keep older people’s skin thicker and more youthful by slowing down the natural thinning of skin layers and protecting the...

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Evidence from Studies

Supporting (1)

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Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults

Randomized Controlled Trial

Human

2025 Dec 20

Contradicting (0)

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults

Score: 77

DOI: 10.1038/s41598-025-32758-5

Similar Assertions

Taking a daily supplement of sodium hyaluronate for 12 weeks can make your cheeks 11.5% and forehead 7.2% more hydrated, and your skin looks and feels healthier.

85%

Taking a daily supplement of sodium hyaluronate for 3 months can make the fine lines around your eyes noticeably smoother—by about 1 in 8 to 1 in 7—starting as soon as one month in.

85%

Taking a daily supplement of hyaluronan for 12 weeks can make your facial wrinkles look about 11.5% less noticeable, compared to not taking anything, if you're a healthy Asian adult between 35 and 64.

78%

Taking a specific type of hyaluronic acid pill every day for 3 months doesn’t make the deeper layer of your skin thicker, which means it probably only works on the top layer.

77%

Taking a daily supplement of hyaluronan for 12 weeks can make your skin feel tighter and more bouncy on your forehead, arms, and waist—especially at your waist, where it improved by 38% compared to people who didn’t take it.

77%