Taking a daily supplement of sodium hyaluronate for 3 months may help keep older people’s skin thicker and more youthful by slowing down the natural thinning of skin layers and protecting the collagen that gives skin its structure.
Claim Language
Language Strength
definitive
Uses definitive language (causes, prevents, cures)
The claim uses the verb 'causes', which implies a direct and certain causal relationship between the intervention and the outcome, without any hedging or probabilistic language.
Context Details
Domain
medicine
Population
human
Subject
Oral sodium hyaluronate (120 mg/day for 12 weeks)
Action
causes
Target
a significant attenuation of age-related decline in dermal density and epidermal thickness in healthy Caucasian adults, preserving collagen content and skin structure
Intervention Details
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.
Evidence from Studies
Supporting (1)
Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults
This study gave people 120 mg of sodium hyaluronate daily for 12 weeks and found their skin got thicker and denser, which is exactly what the claim says — so yes, it supports it.