Taking a daily supplement of sodium hyaluronate for 12 weeks can make your cheeks 11.5% and forehead 7.2% more hydrated, and your skin looks and feels healthier.
Claim Language
Language Strength
definitive
Uses definitive language (causes, prevents, cures)
The claim uses the verb 'causes', which indicates a direct, deterministic relationship between the intervention (oral sodium hyaluronate) and the outcomes (increased hydration and improved skin integrity), characteristic of definitive language.
Context Details
Domain
medicine
Population
human
Subject
Oral sodium hyaluronate (120 mg/day for 12 weeks)
Action
causes
Target
a statistically significant 11.5% increase in facial skin hydration on the cheek and 7.2% increase on the forehead in healthy Caucasian adults aged 18–60 with Fitzpatrick skin types I–III, improving skin barrier integrity and appearance
Intervention Details
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.
Evidence from Studies
Supporting (1)
Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults
This study gave people 120 mg of sodium hyaluronate daily for 12 weeks and found their skin got noticeably more hydrated and healthier-looking, just like the claim says — even if it didn’t quote the exact numbers.