Taking a daily supplement of sodium hyaluronate for 3 months can help your skin hold onto more moisture, especially on your cheeks and forehead, making your skin barrier stronger.

Pro

Against

Evidence from Studies

Supporting (1)

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Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults

Randomized Controlled Trial

Human

2025 Dec 20

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults

Score: 77

DOI: 10.1038/s41598-025-32758-5

Similar Assertions

Taking a daily supplement of hyaluronan for 12 weeks can help your skin hold onto more moisture, making your face less dry — like a natural moisture lock.

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Taking a daily supplement of sodium hyaluronate for 12 weeks can make your cheeks 11.5% and forehead 7.2% more hydrated, and your skin looks and feels healthier.

81%

Taking a daily supplement of hyaluronan for 12 weeks can make your face more hydrated, with a noticeable 10.9% boost in skin moisture compared to not taking it—this also helps your skin stay protected and lose less water.

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Taking a daily supplement of sodium hyaluronate for 3 months may help keep older people’s skin thicker and more youthful by slowing down the natural thinning of skin layers and protecting the collagen that gives skin its structure.

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Taking a daily supplement of sodium hyaluronate for 3 months can make your face skin noticeably more hydrated—about 11.5% more—than if you didn’t take it.

74%