Can a pill make your skin plumper and smoother?
Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
People took a daily pill made of a natural skin substance and their skin got better hydrated, less dry, and had fewer wrinkles — all without creams.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 577 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
People took a daily pill made of a natural skin substance and their skin got better hydrated, less dry, and had fewer wrinkles — all without creams.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 577 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Publication
Authors
Dolečková I, Kušnierik P, Berka V, Šimek M, Matějková I, Prokopec F, Ovesná P
Related Content
Claims (7)
Taking a daily supplement of sodium hyaluronate for 12 weeks can make your cheeks 11.5% and forehead 7.2% more hydrated, and your skin looks and feels healthier.
Taking a daily supplement of sodium hyaluronate for 3 months may help keep older people’s skin thicker and more youthful by slowing down the natural thinning of skin layers and protecting the collagen that gives skin its structure.
Taking a daily supplement of sodium hyaluronate for 3 months can help your skin hold onto more moisture, especially on your cheeks and forehead, making your skin barrier stronger.
Taking a daily supplement of sodium hyaluronate for 3 months can make the fine lines around your eyes noticeably smoother—by about 1 in 8 to 1 in 7—starting as soon as one month in.
Taking a specific supplement called sodium hyaluronate every day for 3 months may boost a natural skin moisturizer called PCA, which could help your skin stay more hydrated.