Taking a specific supplement called sodium hyaluronate every day for 3 months may boost a natural skin moisturizer called PCA, which could help your skin stay more hydrated.

Pro

Against

Evidence from Studies

Supporting (1)

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Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults

Randomized Controlled Trial

Human

2025 Dec 20

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults

Score: 77

DOI: 10.1038/s41598-025-32758-5

Similar Assertions

Taking a daily supplement of sodium hyaluronate for 3 months may help keep older people’s skin thicker and more youthful by slowing down the natural thinning of skin layers and protecting the collagen that gives skin its structure.

75%

Taking a daily supplement of sodium hyaluronate for 12 weeks can make your cheeks 11.5% and forehead 7.2% more hydrated, and your skin looks and feels healthier.

73%

Taking a daily supplement of hyaluronan for 12 weeks can make your face more hydrated, with a noticeable 10.9% boost in skin moisture compared to not taking it—this also helps your skin stay protected and lose less water.

71%

Taking a specific type of hyaluronic acid pill every day for 3 months doesn’t make the deeper layer of your skin thicker, which means it probably only works on the top layer.

71%

Taking a specific type of hyaluronic acid pill every day for 3 months may make the outer layer of your skin thicker, which could help your skin stay healthier and better protected.

71%