Taking a specific type of hyaluronic acid pill every day for 3 months can noticeably reduce the wrinkles around your eyes, according to a study where people who took it had 22% fewer wrinkles than...

Pro

Against

Evidence from Studies

Supporting (1)

Community contributions welcome

Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period

Randomized Controlled Trial

Human

2017

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period

Score: 60

DOI: 10.2147/ccid.s141845

Similar Assertions

People who took a specific type of hyaluronic acid supplement every day for 3 months didn’t show a clear improvement in crow’s feet wrinkles, but there was a tiny hint that it might help—just not enough to be sure.

94%

Taking a daily supplement of hyaluronan for 12 weeks can make your facial wrinkles look about 11.5% less noticeable, compared to not taking anything, if you're a healthy Asian adult between 35 and 64.

82%

Taking a specific hyaluronic acid pill every day for a month can make your skin more hydrated, smoother, and tighter if you're an adult woman showing early signs of aging.

79%

Taking a daily pill of hyaluronic acid for 3 months can make your wrinkles look about 19% smaller than if you didn’t take it, according to this claim.

77%

Taking a daily supplement of hyaluronan for 12 weeks can make your skin feel tighter and more bouncy on your forehead, arms, and waist—especially at your waist, where it improved by 38% compared to people who didn’t take it.

76%