Analysis Version
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History
Back to Study: Altered Oral Nitrate Reduction and Bacterial Profi...
descriptive
34
Pro
0
Against

Researchers wanted to see if differences in mouth bacteria and nitrate-processing ability explain why some people's blood pressure goes down more than others after eating nitrate-rich food.

Scientific Claim

The study investigated whether differences in oral microbiota profiles and oral nitrate-reducing capacity may explain interindividual differences in blood pressure lowering following nitrate supplementation.

Original Statement

“Background: The efficacy of dietary nitrate supplementation to lower blood pressure (BP) in pregnant women is highly variable. We aimed to investigate whether differences in oral microbiota profiles and oral nitrate-reducing capacity may explain interindividual differences in BP lowering following nitrate supplementation.”

From study:Altered Oral Nitrate Reduction and Bacterial Profiles in Hypertensive Women Predict Blood Pressure Lowering Following Acute Dietary Nitrate Supplementation

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

association

Can only show association/correlation

Assessment Explanation

The study describes its research aim without making causal claims. The language 'aimed to investigate whether differences... may explain' appropriately describes the exploratory nature of the study.

Evidence from Studies

Supporting (1)

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34

Altered Oral Nitrate Reduction and Bacterial Profiles in Hypertensive Women Predict Blood Pressure Lowering Following Acute Dietary Nitrate Supplementation

Cross-Sectional Study
Human
2023 Nov

Contradicting (0)

0
No contradicting evidence found

Source Study

Altered Oral Nitrate Reduction and Bacterial Profiles in Hypertensive Women Predict Blood Pressure Lowering Following Acute Dietary Nitrate Supplementation

Score: 34
DOI: 10.1161/HYPERTENSIONAHA.123.21263

Similar Assertions

Researchers studied 55 women (some pregnant, some not, some with high blood pressure, some without) to see how their mouth bacteria and nitrate-processing ability relate to blood pressure changes after eating nitrate-rich food.

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87%

Even when people ate a diet low in nitrate, using the special mouthwash still increased their blood pressure, which suggests the effect comes from the body's own nitrate recycling process.

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85%

The link between oral bacteria that convert nitrates to nitrites and blood pressure is stronger in people who don't have high blood pressure already.

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84%

When mouth bacteria are disrupted, blood pressure goes up regardless of how it's measured - whether at the doctor's office, at home, or with a 24-hour monitor.

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The small blood pressure increase from using the special mouthwash was similar in size to what's known to increase the risk of heart disease and stroke.

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