mechanistic
Analysis v1
Strong Support
Taking a specific amino acid supplement called L-citrulline twice a day for a week helps healthy people with high levels of a certain compound in their blood to produce more of a helpful molecule that improves blood flow.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.
Randomized Controlled Trial
Human
2008 JanThe study gave people a supplement called L-citrulline twice a day for a week and found it boosted a key ratio in their blood that helps make nitric oxide, exactly as the claim says.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.