mechanistic
Analysis v1
Strong Support
Taking a specific amino acid supplement called L-citrulline twice a day for a week can help improve a key balance in your blood that lets your body make more nitric oxide — a molecule that helps your blood vessels relax and work better.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.
Randomized Controlled Trial
Human
2008 JanThe study gave people L-citrulline pills twice a day for a week and found that it raised a key ratio in their blood that helps the body make more nitric oxide—exactly what the claim says.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.