Taking citrulline pills every day for a week at a specific dose doesn't help your body hold onto more protein, even if you're healthy and eating well.

47

Pro

0

Against

Evidence from Studies

Supporting (1)

47

Community contributions welcome

47

Oral citrulline does not affect whole body protein metabolism in healthy human volunteers: results of a prospective, randomized, double-blind, cross-over study.

Randomized Controlled Trial

Human

2011 Dec

Scientists gave healthy people a daily citrulline pill for a week and checked if their bodies held onto more protein — they didn’t. The pill raised some blood chemicals but didn’t help with protein balance.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Oral citrulline does not affect whole body protein metabolism in healthy human volunteers: results of a prospective, randomized, double-blind, cross-over study.

Score: 47

DOI: 10.1016/j.clnu.2011.06.005

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