Taking vitamin D might help your body release a hormone that tells you when you're full and also stop a protein that blocks muscle growth, so you could feel more energized and build muscle more easily.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Retinoic acid and vitamin D(3) powerfully inhibit in vitro leptin secretion by human adipose tissue.

Cross-Sectional Study

Human

2001 Aug

This study found that vitamin D reduces leptin (a fat hormone) in fat tissue in a lab dish, which matches part of the claim. But it didn’t look at muscles or myostatin, so we can’t say if vitamin D helps build muscle like the claim says.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Similar Assertions

When you have more vitamin D in your body, your fat cells send out more of a signal called leptin, which tells your brain you’re full and don’t need to store more fat—so you might gain less fat over time.

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84%

Taking a lot of vitamin D might help your muscles grow bigger by turning down a natural brake that stops them from growing.

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80%

If you make muscle cells produce more of a protein called the vitamin D receptor, the muscles get bigger because they start making more protein, grow more repair cells, and stop a protein that normally limits muscle growth.

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78%

Having more vitamin D in your body might help you build more muscle and store less fat, directing your body’s energy toward making lean tissue instead.

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Two vitamins—retinoic acid and vitamin D3—can reduce the amount of a hormone called leptin that fat tissue releases, and when used together, they work even better than alone.

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