When healthy young men only eat between noon and 8pm for five days straight, their bodies burn fat faster after eating a high-fat meal compared to when they eat throughout the day
Scientific Claim
Five days of time-restricted feeding (12:00-20:00 eating window) increases postprandial fat oxidation rate by approximately 103% effect size (Cohen's dz) compared to a control feeding schedule (8:00-20:00) in healthy young adult males aged 22±1.3 years with BMI 26.0±0.38 kg/m²
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
definitive
Can make definitive causal claims
Assessment Explanation
This is a randomized crossover RCT with direct measurement of postprandial fat oxidation rates. The study design can establish causation for this specific outcome in this specific population.
Source Excerpt
“The postprandial fat oxidation rate of the TRF trial was significantly higher than that of the CON trial (trial × time, p = 0.019; trial, p = 0.004; time, p = 0.256; Fig. 1A). The AUC of postprandial fat oxidation rate in the TRF trial was significantly larger than that of the CON trial (p = 0.02, Fig. 1B). The effect size (Cohen's dz) was 1.03 for the fat oxidation AUC.”
Evidence from Studies
Supporting Evidence (1)
The study measured fat oxidation rates after a high-fat meal in 8 healthy young males. The TRF group showed significantly higher fat oxidation rates during the 4-hour postprandial period (p=0.019) with a large effect size (Cohen's dz=1.03). This is a direct measurement from the study's data.
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