When healthy young men only eat between noon and 8pm for five days straight, it doesn't change their baseline free fatty acid levels
Scientific Claim
Five days of time-restricted feeding (12:00-20:00 eating window) does not significantly affect fasting free fatty acid levels in healthy young adult males aged 22±1.3 years with BMI 26.0±0.38 kg/m²
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
definitive
Can make definitive causal claims
Assessment Explanation
This is a randomized crossover RCT with direct measurement of fasting free fatty acid levels. The study design can establish no effect for this specific outcome in this specific population.
Source Excerpt
“The fasting fat oxidation rate of the time-restricted feeding trial was significantly higher than that of the control trial (p < 0.001). The 24-h energy expenditure, resting energy expenditure, fasting carbohydrate and the concentrations of TG, blood glucose, insulin, free fatty acids, and glycerol between the two trials were not significantly different (p > 0.05) (Table 2).”
Evidence from Studies
Supporting Evidence (1)
The study measured fasting free fatty acid levels in 8 healthy young males. The TRF group showed 0.38±0.17 mmol/L vs 0.35±0.08 mmol/L in the control group (p=0.655), indicating no significant difference. This is a direct measurement from the study's data table.
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