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Back to Study: Kidney-specific genetic deletion of both AMPK α-su...
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Analysis v1
Strong Support

When mice lack the AMPKα1 gene, their kidneys handle salt normally and produce less urine than usual.

8
Pro
0
Against

Evidence from Studies

Supporting (1)

8

Community contributions welcome

8

Kidney-specific genetic deletion of both AMPK α-subunits causes salt and water wasting.

Cohort Study
Animal
2017 Feb 1

Contradicting (0)

0

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No contradicting evidence found

Source Study

Kidney-specific genetic deletion of both AMPK α-subunits causes salt and water wasting.

Score: 8
DOI: 10.1152/ajprenal.00169.2016

Similar Assertions

When mice lose both AMPKα1 and AMPKα2 in their kidneys, they lose too much water and salt in their urine.

8
0
84%

In mice, AMPK is linked to how the kidneys function.

8
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81%

Mice missing the AMPKα1 gene produce more aldosterone in their urine and have lower blood pressure than normal mice.

8
0
77%