Where the ‘kink’ is in the fat molecule decides whether it harms blood vessels — a kink at position 9 or 9+12 is bad, but at position 11 is harmless.

6

Pro

0

Against

Evidence from Studies

Supporting (1)

6

Community contributions welcome

6

Trans Fatty Acids Induce Vascular Inflammation and Reduce Vascular Nitric Oxide Production in Endothelial Cells

Cross-Sectional Study

In Vitro

2011

The study found that some types of trans fats (like those in fried foods) cause inflammation and reduce a helpful molecule in blood vessels, but another type (from dairy) doesn’t—proving it matters where the fat’s double bonds are located.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Trans Fatty Acids Induce Vascular Inflammation and Reduce Vascular Nitric Oxide Production in Endothelial Cells

Score: 6

DOI: 10.1371/journal.pone.0029600

Similar Assertions

Two types of artificial trans fats found in fried and baked foods make blood vessel cells more inflamed and less able to produce a chemical that helps blood vessels relax, but a different trans fat found in dairy doesn’t do this.

6

0

81%

A type of trans fat found naturally in dairy and meat doesn’t harm blood vessel cells in the lab, even though it looks similar to the harmful ones in fried foods.

6

0

73%

These two harmful trans fats cause blood vessel cells to produce excess harmful oxygen molecules, which then trigger inflammation and block the production of a key chemical that keeps blood vessels healthy.

6

0

72%

These two trans fats interfere with how insulin tells blood vessels to relax by blocking key signals in the cell, but other fats don’t have this effect.

6

0

70%