Not all trans fats are the same
Trans Fatty Acids Induce Vascular Inflammation and Reduce Vascular Nitric Oxide Production in Endothelial Cells
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Some trans fats from fried foods hurt blood vessels, but the one from milk and meat doesn't — it's all about where the double bonds are in the fat molecule.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 56 / 44
Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Some trans fats from fried foods hurt blood vessels, but the one from milk and meat doesn't — it's all about where the double bonds are in the fat molecule.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 56 / 44
Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Publication
Authors
Iwata NG, Pham M, Rizzo NO, Cheng AM, Maloney E, Kim F
Related Content
Claims (6)
Industrial hydrogenation of vegetable oils generates trans fatty acids, which are causally linked to increased risk of cardiovascular disease and metabolic dysfunction.
Two types of artificial trans fats found in fried and baked foods make blood vessel cells more inflamed and less able to produce a chemical that helps blood vessels relax, but a different trans fat found in dairy doesn’t do this.
These two harmful trans fats cause blood vessel cells to produce excess harmful oxygen molecules, which then trigger inflammation and block the production of a key chemical that keeps blood vessels healthy.
A type of trans fat found naturally in dairy and meat doesn’t harm blood vessel cells in the lab, even though it looks similar to the harmful ones in fried foods.
Where the ‘kink’ is in the fat molecule decides whether it harms blood vessels — a kink at position 9 or 9+12 is bad, but at position 11 is harmless.