Browse evidence-based analysis of health-related claims and assertions
Log in to see full claim details, scientific mechanisms, and cited studies.
In people aged 70 to 79, the shingles vaccine causes a significant increase in redness, swelling, or soreness at the injection site within a week, which is a normal and expected reaction that...
People who receive the shingles vaccine may have a lower risk of developing dementia, and this reduction in risk appears to be greater for women than for men.
About 1 in 6 people who receive the recombinant shingles vaccine experience fatigue, headache, or fever, which can interfere with their normal daily activities the next day.
One type of shingles vaccine, called the recombinant vaccine, reduces the risk of developing shingles more than the older live attenuated vaccine.
People who have had shingles are at a higher risk of having a stroke in the first month after the infection, with this risk gradually decreasing over the next few months and returning to normal...
People who receive the recombinant shingles vaccine may receive a dementia diagnosis about 164 days later, on average, than those who receive the live attenuated shingles vaccine, with this delay...
People who received the shingles vaccine were observed to have a 20% lower rate of dementia diagnosis over seven years, with this effect being more pronounced in women than in men.
Two different shingles vaccines, Shingrix and Zostavax, are linked to similar levels of reduction in the risk of cardiovascular events.
People who have unhealthy lifestyle habits may experience a stronger reduction in cardiovascular risk after receiving the shingles vaccine compared to those with healthier habits.
People who received the shingles vaccine had a lower rate of heart attacks, strokes, and other serious heart problems over eight years compared to those who did not.
When the varicella-zoster virus becomes active again, it can cause inflammation in blood vessels, which is associated with a higher likelihood of stroke or heart attack.
Neither the newer nor the older shingles vaccine increases the risk of hospitalization, serious illness, or death compared to no vaccine, and neither appears to trigger immune-related diseases more...
The newer shingles vaccine causes more general side effects like headache and muscle pain than no vaccine — about 2.3 times more — but does not cause more systemic reactions than the older vaccine.
The older shingles vaccine, Zostavax, does not significantly reduce the number of confirmed shingles cases compared to no vaccine in adults aged 50 and older.
While the newer shingles vaccine is more effective, it causes significantly more redness, swelling, and pain at the injection site than the older vaccine or no vaccine — about 1.8 times more than...
The newer shingles vaccine, Shingrix, is more effective at preventing shingles than the older vaccine, Zostavax, reducing cases by about 85% compared to Zostavax and 94% compared to no vaccine, but...
The protective effect of the recombinant shingles vaccine against dementia appears to fade over time, with the difference in dementia risk between vaccine groups narrowing after several years, which...
Older adults who received the recombinant shingles vaccine had a lower risk of dementia than those who received flu or Tdap vaccines, indicating that the benefit is not simply from getting any...
People who received the recombinant shingles vaccine were 35% less likely to develop shingles over six years than those who received the older live vaccine, and this benefit was equally strong in men...
Women who received the recombinant shingles vaccine lived 22% longer without a dementia diagnosis than women who received the older live vaccine, while men experienced a smaller 13% increase, and...
Older adults who received the newer recombinant shingles vaccine instead of the older live version lived, on average, 164 more days without a dementia diagnosis over six years, indicating a...
The link between the shingles vaccine and lower dementia risk isn’t due to another policy that started on the same date, because no other health outcomes changed abruptly for people born just before...
The link between the shingles vaccine and lower dementia risk isn’t due to people getting more medical checkups after shingles, because the vaccine didn’t reduce other illnesses and shingles didn’t...
People who received the shingles vaccine were about 37% less likely to develop shingles over seven years, which matches what previous clinical trials have shown, confirming the study’s methods are...