Health Claims

PGC-1alpha plays a key role in how cells manage energy

PGC-1alpha helps change muscle fibers to be better at using oxygen for energy production

PGC-1alpha belongs to a group of proteins that help control gene activity

Because PGC-1alpha helps control fat metabolism, it might be a good target for developing drugs to treat obesity and type 2 diabetes

PGC-1alpha might play a role in diseases like obesity, diabetes, and heart muscle problems

PGC-1alpha helps control how the body uses sugar and fat for energy

PGC-1alpha helps create more mitochondria (cellular power plants) and changes muscle fibers to be better at using oxygen for energy

When it's cold outside, your body makes more PGC-1alpha protein, which helps you generate heat to stay warm

PGC-1alpha is a protein that helps control how cells use energy

People who eat fewer calories for many years have higher levels of a stress hormone called cortisol in their blood compared to people who don't restrict calories or who are endurance athletes, which might be part of a beneficial stress response that helps cells stay healthy.

People who eat fewer calories for many years have more proteins in their muscles that help clean up damaged proteins and cell parts, which might explain why calorie restriction could slow aging.

People who eat fewer calories for many years have higher levels of a stress hormone called cortisol in their blood compared to people who don't restrict calories or who are endurance athletes, which might be a sign of a beneficial stress response.

People who eat fewer calories for many years have more proteins in their muscles that help clean up damaged proteins and cell parts, which may help keep cells healthier.

People who eat fewer calories for many years have less inflammation in their muscles compared to people who don't restrict calories, which may help keep muscles healthier.

People who eat fewer calories for many years have more of a protein called LC3 in their muscles, which is involved in the process of cleaning up damaged cell parts.

People who eat fewer calories for many years have more of a protein called beclin-1 in their muscles, which helps start the process of cleaning up damaged cell parts.

People who eat fewer calories for many years have more of a protein called Grp78 in their muscles, which helps cells deal with stress in the part of the cell that makes proteins.

People who eat fewer calories for many years have more of a protein called HSP70 in their muscles, which helps cells handle stress better.

People who eat fewer calories for many years tend to have higher levels of a stress hormone called cortisol in their blood compared to people who don't restrict calories or who are endurance athletes.

Eating earlier in the day for 4 days didn't change levels of two growth-related hormones in the evening for overweight people compared to eating throughout the day.

Eating earlier in the day for 4 days didn't change levels of two growth-related hormones in the evening for overweight people compared to eating throughout the day.

Eating earlier in the day for 4 days slightly increased a brain-related growth factor in the evening for overweight people compared to eating throughout the day, but this change wasn't statistically significant.

Eating earlier in the day for 4 days lowered cortisol levels in the evening for overweight people compared to eating throughout the day.

Eating earlier in the day for 4 days increased the activity of a gene related to cell growth and metabolism in the evening for overweight people compared to eating throughout the day.