Taking a daily supplement of hyaluronan for 3 months may make your skin look shinier and feel softer, at least according to how people felt about it — but it didn’t work any better than a fake pill.

Evidence from Studies

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Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period

Randomized Controlled Trial

Human

2017

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period

Score: 60

DOI: 10.2147/ccid.s141845

Similar Assertions

Taking a daily supplement of hyaluronan for 12 weeks can make your skin feel tighter and more bouncy on your forehead, arms, and waist—especially at your waist, where it improved by 38% compared to people who didn’t take it.

85%

Taking hyaluronan pills every day for about a month or two may help make dry skin on your face and arms more moisturized, according to studies done on Japanese adults.

84%

Taking a daily supplement of 120 mg of hyaluronan for 3 months can make your face skin feel smoother and less rough, especially if you're a healthy Asian adult between 35 and 64 years old.

84%

Taking a daily supplement of hyaluronan for 12 weeks can make your face more hydrated, with a noticeable 10.9% boost in skin moisture compared to not taking it—this also helps your skin stay protected and lose less water.

83%

Taking a daily supplement of hyaluronan for 12 weeks can make your facial wrinkles look about 11.5% less noticeable, compared to not taking anything, if you're a healthy Asian adult between 35 and 64.

81%