Giving older mice supplements like NR or NMN might help their cells' energy factories work better and handle damage from aging.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Kynurenine pathway, NAD+ synthesis, and mitochondrial function: Targeting tryptophan metabolism to promote longevity and healthspan.

Narrative Review

Animal

2020 Apr

The study looks at boosting NAD+ in mice using supplements like NR or NMN and finds it helps mitochondria work better and protects cells from aging damage, which supports the claim.

Contradicting (0)

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Kynurenine pathway, NAD+ synthesis, and mitochondrial function: Targeting tryptophan metabolism to promote longevity and healthspan.

Score: 1

DOI: 10.1016/j.exger.2020.110841

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