Mice that got the supplement had smaller fat deposits around their organs and under their skin compared to mice that didn't get it.
Scientific Claim
N-acetylcysteine supplementation reduced epididymal and subcutaneous fat pad weights by approximately 1.1g and 1.4g respectively in male C57BL/6 mice fed a high-fat diet compared to untreated high-fat diet mice.
Original Statement
“The results in Fig. 2a show that the NAC treatment significantly blocked the increase of fat pads including epididymal (EWAT) and subcutaneous (SubWAT) adipose tissues in HFD-fed mice by ~1.1 g and ~1.4 g, respectively.”
Evidence Quality Assessment
Claim Status
overstated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study shows an association between NAC and reduced fat pad weights in mice, but cannot prove causation due to study design limitations. The phrase 'significantly blocked' overstates the evidence.
More Accurate Statement
“N-acetylcysteine supplementation was associated with approximately 1.1g and 1.4g reductions in epididymal and subcutaneous fat pad weights respectively in male C57BL/6 mice fed a high-fat diet compared to untreated high-fat diet mice.”
Evidence from Studies
Supporting (1)
N-acetylcysteine Protects Mice from High Fat Diet-induced Metabolic Disorders