Mice with immobilized legs that received MOTS-c had lower levels of key inflammation markers in their blood compared to untreated mice.

MOTS-c reduced levels of several inflammatory proteins in the blood of immobilized mice, which may help reduce muscle damage.

MOTS-c treatment lowered levels of myostatin, a protein that normally limits muscle growth, in immobilized mice.

Mice given MOTS-c had higher levels of the peptide in their blood compared to those without treatment.

MOTS-c helped restore normal activity levels of key muscle proteins (AKT and FOXOs) that are disrupted during immobilization.

MOTS-c lowered levels of myostatin, a protein that inhibits muscle growth, in the muscles of immobilized mice.