Scientists gave male mice a special form of estrogen and they lost weight, but that weight loss didn't make them live longer - female mice also lost weight but didn't get any lifespan benefit from it.

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17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex

Cohort Study

Animal

2021 May

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Source Study

17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex

Score: 13

DOI: 10.1111/acel.13328

Similar Assertions

Scientists gave male mice a special form of estrogen called 17-alpha-estradiol and found that the mice lost about 20% of their body weight, and they stayed lighter the whole time they were being treated.

87%

A special form of estrogen called 17-alpha-estradiol helped male mice live longer, but female mice given the same amount didn't get any lifespan benefit.

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A special form of estrogen given to mice at a specific dose helped male mice live longer, but didn't have the same effect on female mice.

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Scientists fed old male mice a special chemical called 17-α-estradiol and found they lived about 19% longer than mice that didn't get the chemical.

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A special form of estrogen called 17-alpha-estradiol helped male mice live longer when they started taking it in middle age - about 19% longer if started at 16 months old and 11% longer if started at 20 months old. It also increased their maximum lifespan by 7%. But female mice didn't get any lifespan benefit from it at all.

83%