A diabetes drug called tirzepatide can help people lose up to 21% of their body weight, but the weight loss tends to stop increasing too soon — especially for those with type 2 diabetes.

A new weight-loss drug called tirzepatide might help people with obesity lose about 23% of their body weight in a year and a half — possibly even more than some weight-loss surgeries.

People with obesity or type 2 diabetes who take tirzepatide are much more likely to lose a meaningful amount of weight—like 5%, 10%, or even 15% of their body weight—compared to those who don’t, and the more they take, the better the results seem to be.

People with obesity or type 2 diabetes who took a drug called tirzepatide lost a lot of weight—more when they took higher doses—and the effect lasted up to about three years.

A drug called retatrutide probably helps people with obesity or type 2 diabetes lose about 14% of their body weight when given as a weekly shot for up to a year, and higher doses seem to lead to more weight loss.

A drug called retatrutide helps people lose a lot of weight—sometimes over 70 pounds—by targeting certain hormones, but it works so well that it can cause unexpected health problems.