Back to The Most Powerful Peptide for Visceral Belly Fat h
Strong Opposition
assertion
Analysis v1
History

Fat in the liver blocks the body’s ability to manage blood sugar, making it harder to lose weight anywhere else.

13
Pro
71
Against

Evidence from Studies

Supporting (1)

13

Community contributions welcome

13

The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

Randomized Controlled Trial
Animal & In Vitro
2015 Mar 3

Contradicting (4)

71

Community contributions welcome

66

Determinants of delayed or incomplete diphtheria-tetanus-pertussis vaccination in parallel urban and rural birth cohorts of 30,956 infants in Tanzania

Cohort Study
Human
2019 Feb 26
66

Tesamorelin improves fat quality independent of changes in fat quantity

Randomized Controlled Trial
Human
60

The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area in Adults with HIV

Randomized Controlled Trial
Human
2019
10

286-OR: Spatial Regulation of Glucose and Lipid Metabolism by Hepatic Insulin Signaling

Randomized Controlled Trial
Animal

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Similar Assertions

When the front part of the liver doesn’t respond to insulin, the body makes more insulin to try to compensate.

10
0
80%

When the front part of the liver can't respond to insulin, blood sugar goes up—even if the liver makes less fat.

10
0
80%

When the part of the liver that usually responds to insulin is blocked, the liver makes less fat even when the mouse eats a high-fat diet—but its blood sugar and insulin go up instead.

10
0
79%

Where in the liver insulin resistance happens determines whether it causes high blood sugar, high fat, or neither.

10
0
79%

Turning off insulin signals in the back part of the liver cuts fat without making the body pump out more insulin.

10
0
78%

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