Health Claims

For people with type 2 diabetes and kidney problems, taking a weekly semaglutide shot might help slow down how fast their kidneys get worse.

For adults with type 2 diabetes and kidney problems, taking a weekly semaglutide shot (1.0 mg) can lower their chances of serious kidney or heart issues by about a quarter over 3.4 years — about 1 in every 20 people who take it will avoid a major problem.

Turning on a certain brain cell switch (GLP-1) seems to calm brain inflammation in mice with Alzheimer’s or multiple sclerosis, which might help slow down these diseases.

A type of diabetes drug might help protect the brain in diseases like Alzheimer’s and MS by calming brain immune cells and stopping harmful changes in other brain cells.

Turning on a certain brain receptor (called GLP-1) seems to calm down overactive immune cells in the brain and reduce inflammation in animals with diseases like Alzheimer's and Parkinson's — which might help protect brain cells.

Starting diabetes drugs like semaglutide or liraglutide might lower the chance of developing substance use problems, and this seems to be true for people of different ages, weights, races, and types of the drug.

For US veterans with type 2 diabetes and a history of substance use, starting a GLP-1 drug (like Ozempic) may lower their chances of overdosing on drugs or having suicidal thoughts compared to starting a different diabetes drug called an SGLT-2 inhibitor.

For US veterans with type 2 diabetes, taking GLP-1 drugs might help lower the chance of getting hooked on opioids over three years compared to another diabetes drug, SGLT-2 inhibitors — about 1 fewer case for every 1,000 people.

For US veterans with diabetes and substance use issues, taking GLP-1 drugs (like Ozempic) might lower their chances of ending up in the ER, being hospitalized, or dying from substance-related problems compared to those taking a different diabetes drug called SGLT-2 inhibitors.

For US veterans with type 2 diabetes, starting a GLP-1 drug (like Ozempic) might help lower the chance of developing addiction problems—like with alcohol, drugs, or smoking—over three years compared to starting a different diabetes drug called an SGLT-2 inhibitor.

For adults with heart disease and obesity who don’t have diabetes, taking a weekly semaglutide shot (2.4 mg) leads to more than twice as many people stopping treatment because of side effects compared to those taking a dummy shot.

A weekly injection of semaglutide (2.4 mg) helps lower the risk of serious heart problems like heart attack, stroke, or heart-related death by 20% in people over 45 who have heart disease and are overweight, but don’t have diabetes, compared to a fake treatment.

Liraglutide can help treat diabetes, but it might also have serious side effects — so doctors need to think carefully about each person’s health before prescribing it.

The FDA looked at both the good things and the possible risks of a new diabetes drug called liraglutide to decide if it's safe and helpful for patients.

People without diabetes who are overweight or obese and take a weekly 2.4 mg dose of semaglutide often get mild stomach issues like nausea, diarrhea, or vomiting, but most keep taking it — only a small number stop because of these side effects.

If you're an adult with extra weight but don't have diabetes, taking a weekly 2.4 mg shot of semaglutide for about a year and a half can help you lose around 13 kg of fat, including some deep belly fat, while mostly keeping your muscle — even though you might lose a little muscle too, the fat loss is much bigger.

Taking a weekly semaglutide shot (2.4 mg) for about a year helps people with extra weight feel more physically capable and improves their overall quality of life—more than a dummy pill would.

Taking a weekly semaglutide shot (2.4 mg) for about a year and a half can help lower blood pressure, blood sugar, bad cholesterol, and body-wide inflammation in adults with extra weight but no diabetes—better than a placebo.

A weekly shot called semaglutide helped people with extra weight lose nearly 6 inches off their waist over a year and a half, much more than a fake treatment did — which means it may really help reduce belly fat and lower heart and metabolic disease risks.

For adults who aren't diabetic but carry extra weight, a weekly injection of semaglutide (2.4 mg) plus healthy lifestyle changes led to nearly 15% weight loss over a year and a half—way more than lifestyle changes alone.

Diabetes and weight-loss drugs like GLP-1 agonists can lower blood pressure by about 10 points on average, and this happens even before much weight is lost.

Tirzepatide improves cholesterol and fat levels in the blood more than semaglutide, likely because it works on two hormones instead of one.

Some diabetes drugs like liraglutide, semaglutide, and dulaglutide may help protect the heart and lower the chance of serious heart problems in people with type 2 diabetes who already have heart disease — and this benefit might not just be because they lower blood sugar.

A diabetes drug that works on two gut hormones at once (like tirzepatide) lowers blood sugar more than drugs that only target one hormone, reducing HbA1c by over 2 percentage points on average.