Drinking tomato-soy juice increases the amount of specific breakdown products from soy in the urine of adults with obesity, showing that the body metabolizes and absorbs soy compounds effectively.
Mechanism
Synthesis from 1 study
The soy in the juice gets broken down by gut bacteria into smaller pieces, then the liver wraps them in water-friendly molecules so the kidneys can easily flush them out in urine. The urine tests show these exact wrapped molecules increased, proving the whole process happened.
Most probable mechanism
When people drink tomato-soy juice, the soy parts get absorbed from the gut into the blood. Then, bacteria in the gut break down these soy parts into smaller molecules, which the liver changes into water-soluble forms. These changed molecules are filtered by the kidneys and flushed out in urine.
Soy isoflavones are absorbed from the gastrointestinal tract into systemic circulation
Gut microbiota metabolize absorbed isoflavones into compounds such as O-desmethylangolensin and ethylphenol precursors
Liver enzymes conjugate these microbial metabolites with glucuronic acid or sulfate groups to increase water solubility
Conjugated metabolites are filtered by the kidneys and excreted in urine
Evidence from Studies
Supporting (1)
Community contributions welcome
Tomato‐Soy Juice Reduces Inflammation and Modulates the Urinary Metabolome in Adults With Obesity
Contradicting (0)
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Gold Standard Evidence Needed
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